Wanxuan comes from an ordinary family in China and was born in a city near the sea. There are three sisters in the family. She was the youngest, and her second sister was also autistic. We all love the sea. When did Wanxuan’s seizures begin? She had her first attack when she was almost six […]
The holidays are a time to be grateful. During this special time of year, it is also a time of great hope as we look ahead to 2022. This coming year holds the promise of new opportunities and exciting advances in the field of Dravet syndrome. While we expect there will be challenges, I know
Looking Forward With Gratitude and Hope Read More »
Wenxi Yu, PhD – University of Michigan $50,000 ONE YEAR POSTDOCTORAL FELLOWSHIP Co-funded with JAM for Dravet Mutations in the sodium channel genes SCN1A and SCN8A are a significant cause of Developmental Epileptic Encephalopathies (DEEs), severe seizure disorders. We demonstrated that reduced expression of Scn8a using a specific ASO can prevent the onset of seizures
Optimizing the Regional Administration of SCN8a-targeting RNAi Therapy Read More »
Simona Balestrini, MD, PhD – UCL Queen Square Institute of Neurology Sanjay Sisodiya, PhD, FRCP – UCL Queen Square Institute of Neurology $150,000 TWO YEAR CLINICAL RESEARCH AWARD Dravet syndrome (DS) is caused by a genetic change that leads to severe epilepsy with difficult-to-treat seizures, cognitive impairment, other neurological and physical symptoms, and heightened risk
Liu Lin Thio, MD, PhD – Washington University in St. Louis Joel R. Garbow, PhD – Washington University in St. Louis $150,000 TWO YEAR RESEARCH AWARD Co-funded with JAM for Dravet Children with Dravet syndrome have drug-resistant epilepsy characterized by different seizure types along with developmental regression and intellectual impairment. Dravet syndrome is genetic with
Ketogenic Diet Modulated Brain Energy Metabolism in Dravet Syndrome Read More »
Jacy Wagnon, PhD – The Ohio State University College of Medicine $150,000 TWO YEAR RESEARCH AWARD Many individuals with Dravet syndrome (DS) do not achieve adequate seizure control using available drug treatments. These drugs also do not sufficiently treat other symptoms of DS, including behavioral and cognitive impairments. We analyzed gene expression in a mouse
Targeting Molecular Responses to Seizures in Dravet Syndrome Read More »
Manisha N. Patel, PhD – University of ColoradoKelly G. Knupp, MD – Children’s Hospital Colorado $150,000 TWO YEAR RESEARCH AWARD Dravet syndrome (DS) is a catastrophic developmental and epileptic encephalopathy characterized by intractable early-life seizures, and debilitating comorbidities such as cognitive deficits, developmental delay, sleep disturbances, progressive movement abnormalities and increased risk of sudden unexpected
Lymphoblast cell lines as a model to uncover metabolic defects in Dravet syndrome Read More »
Thanksgiving is the perfect time to reflect on the year and what we are thankful for. While nobody’s life is perfect, those of us in the Dravet syndrome patient community definitely have our fair share of struggles and tough days. Sometimes it can be difficult to focus on the positive and have hope for the
I’m Thankful for DSF and the Dravet Community Read More »
SAVE THE DATE! We are so excited to announce that we are planning our 5th DSF Biennial Conference on June 23-25, 2022, in collaboration with Cook Children’s Medical Center in Fort Worth, Texas. We are looking forward to finally seeing our community back in person! This 3-day event is unique in that it is designed
2022 DSF Biennial Conference Read More »
Dravet Syndrome and Social Security Session: Presentation Outline Compassionate Allowance Information Listing 11.02 for Adults Listing 111.02 for Children How Social Security Evaluates Epilepsy under Listing 111.02 Helpful tips for Lay & Medical Statements Teacher Questionnaire Seizure Monitoring Devices Session: Presentation Slides
2021 Day of Dravet Materials Read More »
